微生物群落多样性和结构对深入了解微生物生态系统的功能和多样性至关重要。近年来,基于16S rRNA的分析已成为研究微生物群落多样性和流行预警的重要工具。本文对基于16S rRNA的微生物种群分析研究方法、基本过程及预警关系和目前在预警应用中遇到的问题和改进策略进行分析,为更全面地理解16S rRNA分析方法,特别是其在流行病预警中的作用及利用该系统有效及时地预警流行病的发生提供借鉴。Microbial community diversity and structure are critical to understanding the function and diversity of microbial ecosystems. In recent years, 16S rRNA-based analysis has become an important tool for studying microbial community diversity and epidemic warning. This paper analyzes the research methods, basic processes and early warning relationships of microbial population analysis based on 16S rRNA, as well as the problems encountered in early warning applications and improvement strategies, so as to provide references for a more comprehensive understanding of 16S rRNA analysis methods, especially its role in epidemic early warning and the use of this system to effectively and timely warn the occurrence of epidemic.
