Herein,three novel tetraphenylethylene hydrazone chemosensors TC12,SC16,and TC16 are prepared for the selective detection of F−.Two NH and one C=N units are incorporated into the sensors for better colorimetric responses,whereas the tetraphenyl unit is in charge of the aggregation-induced emission effect.Among them,compounds SC16 and TC16 form stable gels with some organic solvents.All the tetrahydrofuran/H2O solutions of the three compounds exhibit aggregation-induced emission effect,whereby the fluorescence emission increases by varying degrees with the volume of poor solvent water.Moreover,good aggregation-induced emission effects are observed in the self-assembly of SC16 and TC16.As a sample chemosensor,TC12 in tetrahydrofuran responds to F−selectively with high sensitivity,with the colorimetric and fluorometric detection limits of 8.25×10^(−7) mol·L^(-1) and 2.69×10^(−7) mol·L^(-1),respectively.The reversible gel-sol-gel phase transition and color changes indicate that both SC16-dimethyl sulfoxide and TC16-ethyl acetate gels specifically respond to F-with good sensitivity.The detection results are well supported by ultraviolet-visible spectroscopy,fluorescent spectroscopy,and 1H nuclear magnetic resonance.More importantly,the driving forces of gelation are visually clarified through the single crystal X-ray analysis of compound TOMe.
Wenting YinLinqi ShiMengjiao LiangYaodong HuangJunjiao Yang
The development of transition metal complex-based luminescent chemosensors has recently aroused increasing interest for protein biomarker labelling and detection,especially for the real-time diagnosis and treatment of disease.This is owing to their unique photophysical properties,particularly their long-lived and environmentally sensitive emission,which can be easily controlled via the structural modification of ligands.In this overview,we highlight recent examples of protein biomarker detection using group 8–9 metal-based luminescent chemosensors,including the frequently employed ruthenium(II)and iridium(III)complexes.Various mechanisms and sensing modes are described and compared,and the outlook and future directions of this field are discussed as well.
Two novel rhodamine-based fluorescence enhanced molecular probes （RA1 and RA2） were synthesized, which were both designed as comparative fiuoroionophore and chromophore for the optical detection of Hg^2＋. The recognizing behaviors were investigated both experimentally and computationally. They exhibited high selectivity and sensitivity for Hg^2＋ over other commonly coexistent metal ions in CH3CN/H2O （1：1, V/V） solution. Test shows that hydroxy benzene of rich electron was beneficial to the chelate of Hg^2＋ with sensors. The detection limit was measured to be at least 0.14 p.mol/L. After addition of Hg^2＋, the color changed from colourless to pink, which was easily and hydrogel sensor. detected by the naked eye in both solution
