A new fluorescent probe,DQCd2,based on 4-piperidinoquinoline has been synthesized as a fluorescent probe for Cd^2＋.It can ratiometrically respond to Cd^2＋ in PBS buffer by a remarkable emission intensity enhancement（88-fold） and wavelength shift（70 nm）.
A new two-photon fluorescent probe, ADNO, for nitric oxide （NO） based on intramolecular photoinduced electron transfer （PET） mechanism d/splays a rapid response to NO with a remarkable fluorescent enhancement in PBS buffer. The excellent chemoselectivity of ADNO for NO over other ROS/RNS （reactive oxygen species or nitrogen species） and common metal ions was observed. Moreover, ADNO has been successfully applied in fluorescence imaging of NO of living cells using both one-photon microscopy （OPM） and two-~hoton microscopy （TPM）,
