One new sesquiterpene lactone, corialactone E （1）, one new neolignan, coriarianeolignan A （2）, together with three known apocarotenoids （3-5） and one known neolignan （6） have been isolated from a CHCI3 extract of the roots of Coriaria nepalensis. The structures including absolute configurations of 1-6 were elucidated through extensive NMR, HR-ESIMS, and CD data analysis. Structurally, compound I possessed novel variations in the structure, including the newly formed ether ring of C-3/O/C-9 and the lactone ring connecting C-13 and C-5. Compound 5 showed cytotoxic activity against SKOV3 （human ovarian cancer） cells with IC50 values of 4.67 μmol/L. In vivo system, compound 3 showed anti-convulsant activity by 34% at the dose of 5 mg/kg.
One new sesquiterpene compound, namely, illihenlactone A（1）, and one new prenylated C6–C3 compound, illihenryione H（2）, along with three known sesquiterpenes（3–5） were isolated from the stems of Illicium henryi. The structures of 1 and 2 were elucidated by spectroscopic evidence including NMR, HRESIMS and circular dichroism（CD）. Compound 2 exhibited a weak inhibitory ratio for bglucuronidase release induced by platelet-activating factor（PAF） in rat polymorphonuclear leukocytes（PMNs） in vitro.
