Numerical simulations are performed on the interface with large deformation induced by the interaction between a moving shock and two consecutive bubbles. The high performance of the level set method for multi-material interfaces is demonstrated. Discontinuous Galerkin finite element method is used to solve Euleri- an equations. And the fifth-order weighted essentially non-oscillatory （WENO） scheme is used to solve the level set equation for capturing multi-material interfaces. The ghost fluid method is used to deal with the interfacial boundary condition. Results are obtained for two bubble interacting with a moving shock. The contours of the constant density and the pressure at different time are given. In the computational domain, three different cases are considered, i.e. two helium bubbles, a helium bubble followed by an R22 bubble in the direction of the moving shock, and an R22 bubble followed by a helium bubble. Computational results indicate that multi-mate- rial interfaces can be properly captured by the level set method. Therefore, for problems involving the flow of three different materials with two different interfaces, each interface separating two different materials can be similarly handled.
