A novel room-temperature compression molding method combined with particulate leaching was(developed) to fabricate porous polyester scaffolds with the anatomical shape of the tissue or organ potentially(applied) in tissue engineering.Complicated-shaped scaffolds,such as auricle-like ones,were successfully fabricated from compression-molding putty-like mixture of concentrated poly(ε-caprolactone) solution and salt particulate in a mould with a complicated-shaped cavity at room temperature.The resultant porosity can reach over 90%.This room-temperature compression molding method is proven to be very convenient to fabricate three-dimensional porous scaffolds composed of biodegradable polymers.
