目的:综合评价甲状腺自身抗体与慢性荨麻疹发生的相关性。方法:计算机检索The Cochrane Library、PubMed、The Web of Science、EMBase、CNKI、VIP、WanFang Data和Sinomed数据库,搜索有关甲状腺自身抗体与慢性荨麻疹相关性的研究,检索时限均为建库至2018年11月。由2名研究者独立筛选文献、提取资料并对纳入研究的文献进行质量评价,采用Stata 12.0软件进行Meta分析。结果:共纳入25个病例-对照研究,2224例慢性荨麻疹患者,1617例对照者。Meta分析结果显示:与对照组相比,抗甲状腺过氧化物酶抗体(TPO-Ab)阳性( RR =5.290,95 %CI:2.866- 9.766 , P <0.001)和抗甲状腺球蛋白抗体(TG-Ab)阳性( RR =6.229,95 %CI:3.737-10.383, P <0.001)增加慢性荨麻疹患者的发生风险。慢性荨麻疹组中TPO-Ab阳性率和TG-Ab阳性率差不多( OR =1.005,95 %CI:0.820- 1.227 , P =0.959)。亚组分析显示:地区分布及检测方法是结论的重要影响因素。结论:慢性荨麻疹的发病与甲状腺自身抗体存在相关性,但不同抗体之间和慢性荨麻疹的发生无明显差异。研究结果与分布地区和检测方法有关。
Deconstruction and Structuralism are two of the twentieth century western criticism schools, and their relationship still is an issue that needs to be systematically clarified. The paper presents a review study on the particular relationship of Deconstruction and Structuralism by comparing these two criticism schools from the respects of their origins, features, and limitations in the chronological view. It tends to prove that Deconstruction stems from the Structuralism, however Deconstruction differs itself from Structuralism in certain key features and bases itself upon a certain characteristic critique of Structuralism.
