Objective To optimize acupuncture treatment programs for facial paralysis.Methods Sixty-three cases of facial paralysis were randomly grouped according to orthogonal design L9(3)4 table,and treated by different combined programs of 4 factors,A(acupuncture opportunity),B(combination of points),C(stimulating quantity),D(electroacupuncture time) and 3 levels,and changes of the functional score of the facial nerve were observed,and the different combined programs of the 4 factors,A(acupuncture opportunity),B(combination of point),C(stimulating quantity),D(electroacupuncture time) and 3 levels influencing acupuncture therapeutic effect on facial paralysis were optimized.Results B(combination of points) and D(electroacupuncture time) were obvious factors(P0.05),among them,B(combination of points) was the most main influencing factor;among the 3 levels of B(combination of points) and D(electroacupuncture time),B3 (alternately needling two groups of acupoints) and D3 (electroacupuncture treatment at sparse-dense wave for 30 min) were the best.Conclusion Electroacupuncture at sparse-dense wave for 30 min,alternately needling two groups of acupoints is the best program for treatment of facial paralysis.