Objective:To evaluate the anti-aggressive effect of Buspirone in aggressive individuals with DSM-Ⅳ antisocial personality disorder.Methods:The Point-Subtraction Aggression Paradigm(PSAP) and the Modified Overt Aggression Scale (MOAS) were used to assess the anti-aggression effects of Buspirone in a case control study,in which 20 subjects with antisocial personality disorder were included in the study group with Buspirone treatment,and another 20 personality disorder subjects in cotrol group without drug.Results: The efficacy rate of study group assessed with MOAS was 100%,which was significantly higher than that of control group (25%) after four weeks of treatment.The efficacy rate assessed with PSAP-B response and PSAP-B response per point subtraction was 70% and 68.4% in study group,and 50% and 50% in control group.Conclusion:Buspirone treatment has an antiaggressive effect on DSM-Ⅳ antisocial personality disorder subjects.
Objective:To explore and assess the relative factors of responsibility in schizophrenic patients. Method:A self-developed responsibility rating scale for mental illness was used to assess 286 schizophrenic offenders who were divided into three groups according to the different responsibility level. Results: No realistic motivation, impairment of life ability and impairment of reality testing are main relative factors of responsibility assessment for schizophrenic offenders. Conclusion: It is concluded that responsibility rating scale is more effective than experimental evaluation in the assessment of responsibility for schizophrenic offenders.
