Powder metallurgy Ti-45Al-10 Nb alloys was successfully fabricated by reactive sintering of milled powders at 1350 °C for 2 h in vacuum. The microstructure, in particular, constituent phases, grain size, precipitates of the product was investigated in detail. The results indicate that a double phase γ＋α2 microstructure containing Ti2 Al C precipitate is obtained under the sintering condition, and the alloy exhibits a fine and homogenous microstructure compared with traditional Ti Al base. In fine grain structure, the average grain sizes for the γ and α2 phases are（2.3±0.05） and（5.6±0.05） μm, respectively. Additionally, numerous dislocations are observed in the alloy, and the dislocation density in γ phase is significantly higher than that in α2 phase. The formation mechanisms of the dislocation in the present alloy were also discussed in detail.
