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王韩

作品数:5 被引量:44H指数:4
供职机构:湖北中医药大学更多>>
发文基金:湖北省教育科学“十二五”规划课题国家自然科学基金更多>>
相关领域:医药卫生更多>>

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Meta-analysis on protective effect of electroacupuncture at “Nèiguān”(内关 PC 6) in rats with reperfusion injury induced myocardial ischemia被引量:3
2015年
Objective To systematically evaluate the protection effect of electroacupuncture at "Neiguan"(内关 PC 6) on myocardial damage by means of evidence-based medicine.Methods Databases were retrieved by computer,while dissertation compilations and conference proceedings were searched manually.Data were analyzed statistically by using RevMan5.2software.Results Twelve studies were enrolled.Compared with myocardial ischemia reperfusion injury model group,① the magnitude of ECG STⅡ segment elevation can be reduced by means of electroacupuncture at PC 6(WMD=-73.95,95%CI[-109.69,-38.20]) and the difference was statistically significant(P0.0001);② the ATPase in myocardial cells can be increased by means of electroacupuncture at PC 6(SMD=2.28,95%Cl[1.50,3.07]) and the difference was statistically significant(P0.00001);③ the release of cTnT can be reduced by means of electroacupuncture at PC 6(WMD=-2.69,95%CI[-3.16,-2.22]) and the difference was statistically significant(P0.00001);④ the size of myocardial infarction can be reduced by means of electroacupuncture at PC 6(WMD=-17.99,95%Cl[-19.88,-16.09]) and the difference was statistically significant(P0.00001);⑤ the release of CK can be reduced by means of electroacupuncture at PC 6(WMD=-0.44,95%CI[-0.61,-0.27]) and the difference was statistically significant(P0.00001);⑥ the release of CK-MB can be reduced by means of electroacupuncture at PC 6(SMD=-2.85,95%CI[-4.46,-1.24]) and the difference was statistically significant(P0.001);⑦ the release of LDH can be reduced by means of electroacupuncture at PC 6(SMD=-2.97,95%CI[-4.87,-1.07]) and the difference was statistically significant(P0.01).Conclusion Based on the current experimental evidences,electroacupuncture at PC 6 has a higher protective effect on myocardium.
杨会生吴松郑启艳肖晨汐刘晓曼肖雅松易宗毕王韩王一清
关键词:ELECTROACUPUNCTUREMETA-ANALYSIS
联合检测CA724、CA199、CEA对胃癌诊断价值的Meta分析被引量:18
2015年
[目的]系统评价联合检测血清肿瘤标志物(CA724、CA199、CEA)对胃癌的诊断价值。[方法]计算机检索Pub Med、中国知网、万方、维普等数据库,收集关于CA724、CA199、CEA在胃癌诊断中应用的相关文献。采用Meta-Disc l.4、Rev Man 5.2和Stata 13.0进行Meta分析。[结果]纳入10篇文献,共1642例。对胃癌诊断中,单独检测CA724的敏感度为0.49(95%CI:0.45~0.53),特异度为0.91(95%CI:0.89~0.93),诊断比值比为10.97(95%CI:8.22~14.63);联合检测的敏感度为0.76(95%CI:0.73~0.79),特异度为0.82(95%CI:0.79~0.84),诊断比值比为19.85(95%CI:10.78~36.52)。单独检测CA724的曲线下面积(AUC)=0.80,Q*=0.74;联合检测的AUC=0.95,Q*=0.90。联合检测和单独检测CA724两种方式的诊断效能差异具有统计学意义(Z=4.86,P〈0.05)。[结论]CA724联合检测的诊断效能比单独检测CA724要高,对胃癌的辅助诊断具有较高的指导意义。
杨会生王韩汤宛莹李薇薇郑启艳易宗毕龚红卫
关键词:CA724CA199CEA胃肿瘤META分析
不同腧穴配伍对颈型颈椎病患者体表肌电即时效应的影响被引量:11
2017年
目的:观察不同腧穴配伍对颈型颈椎病患者体表肌电即时效应的影响,探讨腧穴配伍之间的相互作用及规律。方法:90例颈型颈椎病患者前后进行3种不同腧穴配伍的针刺,远部取穴组(A组:昆仑、后溪);近部取穴组(B组:风池、天柱);远近取穴组(C组:昆仑、后溪、风池、天柱),采用自身前后对照,观察针刺前后体表肌电(Surface Electromyography,SEMG)平均振幅值,测量肌电积分(Integrated Electromyography,IEMG)及肌电均方根(Root Mean Square,RMS)均值,计算肌电振幅变化率,组内比较不同腧穴配伍针刺前后对体表肌电即时效应影响的差异,组间比较各组针刺后差异。结果:组内针刺前后比较,A、B、C组的肌电平均振幅值、肌电振幅变化率、IEMG、RMS差异有统计学意义(P<0.05)。组间针刺后比较,A、B、C组针刺后肌电平均振幅值、肌电振幅变化率、IEMG、RMS都有不同程度的改变,但无显著性差异(P>0.05)。结论:不同腧穴配伍的针刺治疗均可以明显改善颈部前屈的耐疲劳性;针刺对颈型颈椎病的治疗作用与取穴数目的多少无关,并不能简单地认为腧穴配伍越多,疗效就会越好。
杨会生郑启艳杜彦仪吴林刘甜王韩戴文康吴松
关键词:腧穴配伍颈型颈椎病
Influence of different acupoint combinations on immediate effect of surface electromyography of patients with cervical spondylosis被引量:4
2016年
Objective To observe the influence of different acupoint combinations on immediate effect of surface electromyography of patients with cervical spondylosis, and to explore the interactions and laws among different acupoint combinations. Methods Acupuncture in three kinds of different acupoint combinations was conducted on 90 patients with cervical spondylosis(three groups): group A [distal point selection group: Kūnlún(昆仑 BL 60) and Hòuxī(后溪 SI 3)]; group B [local point selection group: Fēngchí(风池 GB 20) and Tiānzhù(天柱 BL 10)]; group C(distal and local point selection group: BL 60, SI 3, GB 20 and BL 10). Self control before and after treatment was adopted to observe the mean value of surface electromyography(SEMG) amplitude, to measure the mean values of integrated electromyography(IEMG) and electromyography root mean square(RMS), and to calculate the variation rate of electromyography amplitude of trapezius on the affected side of patients before and after acupuncture. The differences of influences of different acupoint combinations on immediate effect of surface electromyography were compared intra-group, and the differences among the three groups after acupuncture were also compared. Results According to the intragroup comparison before and after acupuncture, the differences of mean value of electromyography amplitude, variation rate of electromyography amplitude, IEMG and RMS were both statistically significant(all P〈0.05). According to the inter-group comparison after acupuncture, the mean value of electromyography amplitude, variation rate of electromyography amplitude, IEMG and RMS varied in different degrees, however, the differences were not significant(all P〉0.05); there was no significant difference in the total effective rate among the three groups(P〉0.05). Conclusion Acupuncture treatment in different acupoint combinations can increase IEMG and RMS and reduce mean value of electromyography amplitude and variation r
杨会生郑启艳杜彦仪吴林刘甜王韩戴文康吴松
针灸治疗2型糖尿病的Meta分析被引量:8
2016年
目的系统评价针灸治疗2型糖尿病(T2DM)的疗效和安全性。方法计算机检索相关文献,按照制定的标准筛选后,由2名研究者单独提取资料、交叉核对,将数据录入Rev Man5.2作统计分析。结果共纳入9个研究,共743例患者。Meta分析结果表明1比较治疗后的总有效率,单纯针灸或针药联合治疗高于对照组[OR=3.60,95%CI(2.11,6.13)],差异具有统计学意义(Z=4.71,P<0.00001)。2比较治疗后的空腹血糖(FPG),试验组血糖降低幅度明显大于对照组[WMD=-1.20,95%CI(-1.38,-1.02)],差异具有统计学意义(Z=12.88,P<0.00001)。3比较治疗后的餐后2 h血糖(P2h PG),试验组血糖降低幅度明显大于对照组[WMD=-1.27,95%CI(-1.47,-1.06)],差异具有统计学意义(Z=12.02,P<0.00001)。结论针灸或针药联合治疗T2DM的临床效果显著优于单纯的中药或西药治疗,且无毒副反应。
郑启艳杨会生项蓉蓉杜彦仪卢琴张育硕王韩吴松
关键词:针灸疗法META分析随机对照试验
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