The pinching of n-dimensional closed hypersurface Mwith constant mean curvature H in unit sphere S^（n＋1）（ 1） is considered. Let A = ∑i,j,k h（ijk）~2（ λi＋ nH）~2,B = ∑i,j,k h（ijk）~2（ λi＋ nH） ·（ λj＋ nH）,S = ∑i（ λi＋ nH）~2, where h（ij）= λiδ（ij）. Utilizing Lagrange＇s method, a sharper pointwise estimation of 3（A- 2B） in terms of S and ｜▽h｜~2 is obtained, here ｜▽h｜~2= ∑i,j,k h（ijk）~2. Then, with the help of this, it is proved that Mis isometric to the Clifford hypersurface if the square norm of the second fundamental form of Msatisfies certain conditions. Hence, the pinching result of the minimal hypersurface is extended to the hypersurface with constant mean curvature case.
