搜索到1133篇“ MULTIPARAMETER“的相关文章
Multiparameter magnetic resonance imaging-based radiomics model for the prediction of rectal cancer metachronous liver metastasis
2025年
BACKGROUND The liver,as the main target organ for hematogenous metastasis of colorectal cancer,early and accurate prediction of liver metastasis is crucial for the diagnosis and treatment of patients.Herein,this study aims to investigate the application value of a combined machine learning(ML)based model based on the multiparameter magnetic resonance imaging for prediction of rectal metachronous liver metastasis(MLM).AIM To investigate the efficacy of radiomics based on multiparametric magnetic resonance imaging images of preoperative first diagnosed rectal cancer in predicting MLM from rectal cancer.METHODS We retrospectively analyzed 301 patients with rectal cancer confirmed by surgical pathology at Jingzhou Central Hospital from January 2017 to December 2023.All participants were randomly assigned to the training or validation queue in a 7:3 ratio.We first apply generalized linear regression model(GLRM)and random forest model(RFM)algorithm to construct an MLM prediction model in the training queue,and evaluate the discriminative power of the MLM prediction model using area under curve(AUC)and decision curve analysis(DCA).Then,the robustness and generalizability of the MLM prediction model were evaluated based on the internal validation set between the validation queue groups.RESULTS Among the 301 patients included in the study,16.28%were ultimately diagnosed with MLM through pathological examination.Multivariate analysis showed that carcinoembryonic antigen,and magnetic resonance imaging radiomics were independent predictors of MLM.Then,the GLRM prediction model was developed with a comprehensive nomogram to achieve satisfactory differentiation.The prediction performance of GLRM in the training and validation queue was 0.765[95%confidence interval(CI):0.710-0.820]and 0.767(95%CI:0.712-0.822),respectively.Compared with GLRM,RFM achieved superior performance with AUC of 0.919(95%CI:0.868-0.970)and 0.901(95%CI:0.850-0.952)in the training and validation queue,respectively.The DCA indicated that the predictive abil
Zhi-Da LongXiao YuZhi-Xiang XingRui Wang
多参数MRI在前列腺癌与前列腺炎鉴别诊断中的应用研究
2024年
目的探究多参数MRI(Mp-MRI)在前列腺癌与前列腺炎鉴别诊断中的应用价值。方法选取2020年1月至2023年1月医院收治的78例前列腺病变患者作为研究对象,均接受Mp-MRI检查。以病理检查结果为金标准,分析Mp-MRI对前列腺癌与前列腺炎的鉴别诊断价值,以及前列腺癌组与前列腺炎组的Mp-MRI参数、成像特征。结果病理检查结果显示,78例患者中前列腺癌50例,前列腺炎28例。以病理检查结果为金标准,Mp-MRI的诊断灵敏度为96.00%,特异度为92.86%。Mp-MRI影像显示,前列腺癌组的表观扩散系数(ADC)低于前列腺炎组,信号强度-时间曲线(ST-T)参数中强化峰值高于前列腺炎组,到达增强峰值时间短于前列腺炎组,差异均有统计学意义(P<0.05);前列腺癌病灶多为单侧,而前列腺炎病灶多为双侧,差异有统计学意义(P<0.05);两组的局灶非结节低信号检出率比较,差异无统计学意义(P>0.05);前列腺癌组的局灶结节状低信号、占位信号检出率高于前列腺炎组,弥漫性低信号、患侧外周带肿胀检出率低于前列腺炎组,差异均有统计学意义(P<0.05)。结论Mp-MRI对前列腺癌与前列腺炎的诊断灵敏度、特异度均较高,可通过不同参数与成像特征进行鉴别诊断。
李佳敏俞丽燕
关键词:前列腺癌前列腺炎
Multiparameter collaborative optimization of the vibrating screen based on the behavior of oil sunflower seed penetrating screen holes
2024年
The behavior of oil sunflower seeds penetrating screen holes is an important factor that affects the screening performance of oil sunflower seeds.In this study,a double-deck reverse-motion vibrating screening device for oil sunflower seed screening was designed.The force condition and motion law of the oil sunflower seeds on the screen surface were analyzed.This study compared the effect of particle filling amount of discrete element model of oil sunflower seeds on the simulation effects.The screening process was numerically simulated using the coupled Discrete Element Method and Multibody Dynamics(DEM-MBD)technique with the screening percentage of oil sunflower seeds as the index.The influence of the operating parameters of the vibrating screen on the screening effect was analyzed using a multiparameter collaborative optimization scheme.The results of this study can provide a reference for the numerical simulation of crop screening behavior and the development of screening devices.
Wenbo WeiJianchang LiJianjun HaoMaohua XiaoHuiju Zhang
多参数流式细胞技术分析髓系白血病细胞相关免疫表型
2024年
目的 探讨常见的急性髓系白血病细胞相关免疫表型,并阐述其在临床中的应用价值。方法 应用多参数流式细胞技术分析47例急性髓系白血病(AML)患者骨髓标本中白血病细胞相关免疫表型,并对其免疫分型结果与治疗、预后的相关性进行统计分析,进而探讨AML免疫分型在临床中的应用。结果 47例AML患者阳性高表达的髓系抗原有CD33(93.62%)、CD13(89.36%)、MPO(89.36%)、CD117(82.98%)、CD64(38.30%);造血干/祖细胞CD分子阳性表达以CD38(93.62%)、CD34(65.96%)、HLA-DR(51.06%)为主;其他抗原以CD56(48.94%)、CD7(23.40%)、CD19(19.15%)为主。经相同时间治疗后,23例(48.94%)AML患者病情得到完全缓解,患者阳性表达T细胞系抗原CD7的完全缓解率显著低于阴性患者(P<0.05)。6例(26.09%)患者在1 a内复发,没有任何一种抗原表达情况与之有关(P>0.05)。随访结束后,有26例(55.32%)患者死亡,阳性表达NK细胞系抗原CD56和T细胞系抗原CD7患者的死亡率显著性高于阴性表达的患者,阳性表达B细胞系抗原CD19的患者死亡率显著性低于阴性表达的患者(P<0.05),幼稚标志与成熟标志不同步的患者死亡率高于幼稚标志与成熟标志同步的患者(P<0.05)。结论 髓系抗原CD33、CD13、MPO、CD117、CD64是AML诊断中可靠的抗原标志物,AML患者的免疫分型结果可为临床医生确定治疗方案和判断预后提供参考。
王艺潼姜佳彤吴金娜刘天月武风云宋玉国
关键词:CD分子
Application of texture signatures based on multiparameter-magnetic resonance imaging for predicting microvascular invasion in hepatocellular carcinoma:Retrospective study
2024年
BACKGROUND Despite continuous changes in treatment methods,the survival rate for advanced hepatocellular carcinoma(HCC)patients remains low,highlighting the importance of diagnostic methods for HCC.AIM To explore the efficacy of texture analysis based on multi-parametric magnetic resonance(MR)imaging(MRI)in predicting microvascular invasion(MVI)in preoperative HCC.METHODS This study included 105 patients with pathologically confirmed HCC,categorized into MVI-positive and MVI-negative groups.We employed Original Data Analysis,Principal Component Analysis,Linear Discriminant Analysis(LDA),and Non-LDA(NDA)for texture analysis using multi-parametric MR images to predict preoperative MVI.The effectiveness of texture analysis was determined using the B11 program of the MaZda4.6 software,with results expressed as the misjudgment rate(MCR).RESULTS Texture analysis using multi-parametric MRI,particularly the MI+PA+F dimensionality reduction method combined with NDA discrimination,demonstrated the most effective prediction of MVI in HCC.Prediction accuracy in the pulse and equilibrium phases was 83.81%.MCRs for the combination of T2-weighted imaging(T2WI),arterial phase,portal venous phase,and equilibrium phase were 22.86%,16.19%,20.95%,and 20.95%,respectively.The area under the curve for predicting MVI positivity was 0.844,with a sensitivity of 77.19%and specificity of 91.67%.CONCLUSION Texture analysis of arterial phase images demonstrated superior predictive efficacy for MVI in HCC compared to T2WI,portal venous,and equilibrium phases.This study provides an objective,non-invasive method for preoperative prediction of MVI,offering a theoretical foundation for the selection of clinical therapy.
Hai-Yang NongYong-Yi CenMi QinWen-Qi QinYou-Xiang XieLin LiMan-Rong LiuKe Ding
Multiparameter performance monitoring of pulse amplitude modulation channels using convolutional neural networks
2024年
A designed visual geometry group(VGG)-based convolutional neural network(CNN)model with small computational cost and high accuracy is utilized to monitor pulse amplitude modulation-based intensity modulation and direct detection channel performance using eye diagram measurements.Experimental results show that the proposed technique can achieve a high accuracy in jointly monitoring modulation format,probabilistic shaping,roll-off factor,baud rate,optical signal-to-noise ratio,and chromatic dispersion.The designed VGG-based CNN model outperforms the other four traditional machine-learning methods in different scenarios.Furthermore,the multitask learning model combined with MobileNet CNN is designed to improve the flexibility of the network.Compared with the designed VGG-based CNN,the MobileNet-based MTL does not need to train all the classes,and it can simultaneously monitor single parameter or multiple parameters without sacrificing accuracy,indicating great potential in various monitoring scenarios.
Si-Ao LiYuanpeng LiuYiwen ZhangWenqian ZhaoTongying ShiXiao HanIvan B.DjordjevicChangjing BaoZhongqi PanYang Yue
An integrated micromachined flexible ultrasonicinductive sensor for pipe contaminant multiparameter detection
2024年
Pipe contaminant detection holds considerable importance within various industries,such as the aviation,maritime,medicine,and other pertinent fields.This capability is beneficial for forecasting equipment potential failures,ascertaining operational situations,timely maintenance,and lifespan prediction.However,the majority of existing methods operate offline,and the detectable parameters online are relatively singular.This constraint hampers real-time on-site detection and comprehensive assessments of equipment status.To address these challenges,this paper proposes a sensing method that integrates an ultrasonic unit and an electromagnetic inductive unit for the real-time detection of diverse contaminants and flow rates within a pipeline.The ultrasonic unit comprises a flexible transducer patch fabricated through micromachining technology,which can not only make installation easier but also focus the sound field.Moreover,the sensing unit incorporates three symmetrical solenoid coils.Through a comprehensive analysis of ultrasonic and induction signals,the proposed method can be used to effectively discriminate magnetic metal particles(e.g.,iron),nonmagnetic metal particles(e.g.,copper),nonmetallic particles(e.g.,ceramics),and bubbles.This inclusive categorization encompasses nearly all types of contaminants that may be present in a pipeline.Furthermore,the fluid velocity can be determined through the ultrasonic Doppler frequency shift.The efficacy of the proposed detection principle has been validated by mathematical models and finite element simulations.Various contaminants with diverse velocities were systematically tested within a 14mm diameter pipe.The experimental results demonstrate that the proposed sensor can effectively detect contaminants within the 0.5−3mm range,accurately distinguish contaminant types,and measure flow velocity.
Zheng YuanXiaoyu WuZhikang LiJiawei YuanYihe ZhaoZixuan LiShaohui QinQi MaXuan ShiZilong ZhaoJiazhu LiShiwang ZhangWeixuan JingXiaozhang WangLibo Zhao
关键词:INDUCTIVEULTRASONIC
多参数磁共振成像技术对外周带早期前列腺癌和前列腺炎的鉴别诊断价值被引量:3
2024年
目的分析多参数磁共振成像技术对外周带早期前列腺癌和前列腺炎的鉴别诊断价值。方法以我院2019年5月至2022年12月收治的31例疑似外周带早期前列腺癌和59例疑似前列腺炎患者为本次研究对象。所有研究对象入院后先开展磁共振成像检查,再开展多参数磁共振成像检查。参考金标准,比较两种检查方法对外周带早期前列腺癌及前列腺炎的诊断效能。结果多参数磁共振成像技术对外周带早期前列腺癌及前列腺炎的诊断准确度、特异度显著高于磁共振成像技术(P<0.05)。两种检查方法对外周带早期前列腺癌及前列腺炎的诊断灵敏度无显著差异(P>0.05)。结论多参数磁共振成像技术可有效提高外周带早期前列腺癌和前列腺炎患者的疾病诊断准确度,为患者的早期治疗提供可靠依据。
马铭婕
关键词:前列腺炎
基于钻孔多参数测井的煤层顶底板岩性及厚度识别
2024年
【背景】在煤层开采过程中,有效的地层特征探测方法对于井下工作开展至关重要,精确掌握煤层及其顶底板围岩的地层特征信息,有助于煤层瓦斯治理,保障矿井安全高效生产。【方法】采用底抽巷穿层钻孔进行多参数测井,重点分析了低位上行钻孔轨迹信息与自然伽马、自然电位和电阻率等参数的变化特性;通过综合对比多个钻孔的轨迹数据钻孔视频成像和测井结果,详细描述了工作面煤层及周围岩层的分布特征,并准确界定了各岩石类型及其真厚度;基于钻孔测井曲线特征和对应区域成孔视频,识别煤层中煤体结构异常区域和煤层含水区域。【结果和结论】研究结果表明:研究区域煤层顶底板岩性主要包括砂质泥岩、泥岩、细砂岩、煤4种岩石,不同岩性具有显著的测井响应特征,结合岩性划分结果和对应的钻孔轨迹信息,能有效划分煤层及其顶底板围岩层位。对单个钻孔开展重复性测井,提高了岩石岩性和厚度的识别精度,孔内厚度测量误差控制在0.2 m内,验证了测井结果的可靠性。煤层自然电位和电阻率曲线交会图表明,底抽巷第三、第四组钻孔之间存在长8.4 m,厚1.1 m的煤体结构异常区域;自然伽马、电阻率曲线交会图曲线和钻孔视频表明,第6组钻孔间存在长3.4 m,厚0.9 m的含水区域,研究结果与工作面瞬变电磁法勘测结果相一致,区域表现为弱富水性。多参数测井为快速判别井下钻孔的目标层位提供了高效手段,在推进矿井地质信息的透明化建设上有着良好的应用前景。
李哲高保彬雷文杰李东会李东会
关键词:钻孔轨迹岩石类型岩性划分测井曲线
基于多参数磁共振的影像组学模型预测前列腺癌Ki67的表达
2024年
目的基于多参数磁共振建立影像组学模型预测前列腺癌Ki67的表达。方法回顾性分析我院2020年12月1日~2023年6月30日经病理证实、磁共振数据完成的PCa患者176例,按照7:3的比例分配到训练组(n=140)及验证组(n=36)。从PACS工作站中导出患者T2加权成像、T2加权脂肪抑制成像、小视野扩散加权成像、表观扩散系数的DICOM图像,在4个序列图像中勾画出病变区域的三维感兴趣区,并提取其中的影像组学特征,使用Spearman相关系数和LASSO回归对特征进行降维和选择,利用筛选出的组学特征建立影像组学模型。利用绘制ROC曲线并计算曲线下面积(AUC),阐述模型的诊断意义,并通过验证组对诊断效能施行验证。结果共提取1834个影像组学特征,最终筛选得到20个组学特征与Ki67表达状态相关。在互相独立创建的8个影像组学模型中,分别为逻辑回归、支持向量机、K-近邻、随机森林、极度随机树、极致梯度提升、轻量级梯度提升机和多层感知机,此中轻量级梯度提升机模型效益最优,训练组的AUC值为0.948(95%CI:0.913~0.982),测试组的AUC值为0.832(95%CI:0.698~0.967)。结论基于多参数磁共振构建的影像组学模型可以预测Ki67表达状况,且轻量级梯度提升机模型最好。
翟承凤何永胜戚轩杨宏楷杨馨
关键词:前列腺癌KI67